Functional MRI (fMRI) is an advanced brain imaging technique that allows us to detect the brain area activated by a task. What are its clinical applications ?

Brain Tumors

• Stippich et al. Localizing and Lateralizing Language in Patients with Brain Tumors: Feasibility of Routine Preoperative Functional MR Imaging in 81 Consecutive Patients. Radiology (2007) 243(3): 828-836.

fMRI in vegetative patients

• Di et al. Cerebral response to patient's own name in the vegetative and minimally conscious states. Neurology 2007, 68:895-899.
• Giacino. Disorders of consciousness: differential diagnosis and neuropathologic features. Semin.Neurol. 1997, 17:105-111.
• Giacino et al. The minimally conscious state: definition and diagnostic criteria. Neurology 2002, 58:349-353.
• Giacino. The vegetative and minimally conscious states: consensus-based criteria for establishing diagnosis and prognosis. NeuroRehabilitation. 2004, 19:293-298.
• Monti et al. Willful Modulation of Brain Activity in Disorders of Consciousness. NEJM 2010.
• Owen et al. Detecting awareness in the vegetative state. Science 2006, 313:1402.
• Schiff et al. fMRI reveals large-scale network activation in minimally conscious patients. Neurology 2005, 64:514-523.
• Vanhaudenhuyse et al. Default network connectivity reflects the level of consciousness in non-communicative brain damaged patients. Brain 2010, 133:161-171.

Neuromarketing

• Glimcher and Rustichini. Neuroeconomics: the consilience of brain and decision. Science 2004, 306:447-452.
• Lee, Broderick, and Chamberlain. What is "neuromarketing"? A discussion and agenda for future research. Int.J.Psychophysiol. 2007, 63:199-204.
• McClure et al. Neural correlates of behavioral preference for culturally familiar drinks. Neuron 2004, 44:379-387.

Lie detection

• McMahon. Polygraph testing for deception in Australia: effective aid to crime investigation and adjudication? J.Law Med. 2003, 11:24-47.
• Lee et al. Lie detection by functional magnetic resonance imaging. Hum.Brain Mapp. 2002, 15:157-164.
• Mohamed et al. Brain mapping of deception and truth telling about an ecologically valid situation: functional MR imaging and polygraph investigation--initial experience. Radiology 2006, 238:679-688.
• Davatzikos et al. Classifying spatial patterns of brain activity with machine learning methods: application to lie detection. Neuroimage. 2005, 28:663-668.

Mind Reading

• Hassabis et al. Decoding Neuronal Ensembles in the Human Hippocampus. Current Biology 2009, 19:546-554.
• Haynes et al. Reading Hidden Intentions in the Human Brain. Current Biology 2007, 17:323-328.
• Kay et al. Identifying natural images from human brain activity. Nature 2008, 452:352-355.

fMRI of Sex

• Hamann et al. Men and women differ in amygdala response to visual sexual stimuli. Nat Neurosci. 2004, 7:411-416.
• Holstege et al. Brain activation during human male ejaculation. The Journal of Neuroscience 2003, 23:9185-9193.
• Karama et al. Areas of brain activation in males and females during viewing of erotic film excerpts. Hum Brain Mapp. 2002, 16:1-13.
• Maravilla et al. Sex and the brain: the role of fMRI for assessment of sexual function and response. Int J Impot Res. 2007, 19:25-29.
• Takahashi et al. Men and women show distinct brain activations during imagery of sexual and emotional infidelity. Neuroimage 2006, 32:1299-1307.

fMRI of Piano Players

• Stewart et al. A neurocognitive approach to music reading. Ann N Y Acad Sci. 2005, 1060:377-86.
• Meister at al. Playing piano in the mind--an fMRI study on music imagery and performance in pianists. Brain Res Cogn Brain Res. 2004, 19:219-28.)
• Bengtsson et al. Dissociation between melodic and rhythmic processing during piano performance from musical scores. Neuroimage 2006, 30:272-84.

Perfusion MRI is a neuroimaging technique which can measure the local perfusion of brain tissues.